Fig. 5. Effect of magnesium oxide (MgO) on gastrointestinal symptoms in Japanese patients with chronic constipation. (C) The severity score for straining during defecation in the placebo group did not differ before versus after taking the drug, although there was significant improvement in the MgO group (P = 0.003). The 2 groups did not show any statistically significant differences in terms of (A) abdominal bloating, (B) abdominal discomfort, or (D) sensation of incomplete evacuation.
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