Fig. 1. Exemplars of nighttime metabolites across 4 time periods between healthy controls (HCs) and women with irritable bowel syndrome (IBS). T1 represents 20:00 and 21:20 (awake); T2 represents 22:40 and 24:00 (transition from wake to sleep); T3 represents 01:20 and 02:40 (early sleep); and T4 04:00 and 05:20 (mid to late sleep). G, group; T, time; NS, not significant (P > 0.25). *Group effect at each time point (P < 0.05). Y axis: log transformed metabolites.
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