Fig. 1. Manometric protocol. The study was done in two separated days and all patients were required to stop nitrites or calcium channel blocker, if taken, for 24 hours. On the first day, patients were asked to swallow 5 mL of room-temperature water three times and rest for 15 minutes. After that, patients were required to swallow hot water (50℃) 10 mL and rest for 30 seconds. Finally, patients made the last three swallows of hot water (50℃), 5 mL each time. Procedure on the second day was approximately the same as the first day, with "Hot" water replaced by "Iced" water (2℃). RT, room temperature.
© J Neurogastroenterol Motil
