Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Cited by CrossRef (54)

  1. Edward Walker, Kim Lo, Sze Tham, Malcolm Pahl, Dominic Lomiwes, Janine Cooney, Mark Wohlers, Pramod Gopal. New Zealand Bitter Hops Extract Reduces Hunger During a 24 h Water Only Fast. Nutrients 2019;11:2754
    https://doi.org/10.3390/nu11112754
  2. Andrew J. Taylor, Jonathan D. Beauchamp, Loïc Briand, Martina Heer, Thomas Hummel, Christian Margot, Scott McGrane, Serge Pieters, Paola Pittia, Charles Spence. Factors affecting flavor perception in space: Does the spacecraft environment influence food intake by astronauts?. Comp Rev Food Sci Food Safe 2020;19:3439
    https://doi.org/10.1111/1541-4337.12633
  3. Eveline Deloose, Pieter Janssen, Maura Corsetti, Jessica Biesiekierski, Imke Masuy, Alessandra Rotondo, Lukas Van Oudenhove, Inge Depoortere, Jan Tack. Intragastric infusion of denatonium benzoate attenuates interdigestive gastric motility and hunger scores in healthy female volunteers. The American Journal of Clinical Nutrition 2017;105:580
    https://doi.org/10.3945/ajcn.116.138297
  4. Jennifer Wilbrink, Gwen Masclee, Tim Klaassen, Mark van Avesaat, Daniel Keszthelyi, Adrian Masclee. Review on the Regional Effects of Gastrointestinal Luminal Stimulation on Appetite and Energy Intake: (Pre)clinical Observations. Nutrients 2021;13:1601
    https://doi.org/10.3390/nu13051601
  5. Greanious Alfred Mavondo, Blessing Nkazimulo Mkhwananzi, Musa Vuyisile Mabandla. Pre-infection administration of asiatic acid retards parasitaemia induction in Plasmodium berghei murine malaria infected Sprague-Dawley rats. Malar J 2016;15
    https://doi.org/10.1186/s12936-016-1278-6
  6. Elisabetta Schiano, Fortuna Iannuzzo, Mariano Stornaiuolo, Fabrizia Guerra, Gian Carlo Tenore, Ettore Novellino. Gengricin®: A Nutraceutical Formulation for Appetite Control and Therapeutic Weight Management in Adults Who Are Overweight/Obese. IJMS 2024;25:2596
    https://doi.org/10.3390/ijms25052596
  7. Martina Chiurazzi, Barbara De Conno, Mariastella Di Lauro, Bruna Guida, Gilda Nasti, Elisabetta Schiano, Mariano Stornaiuolo, Gian Carlo Tenore, Antonio Colantuoni, Ettore Novellino. The Effects of a Cinchona Supplementation on Satiety, Weight Loss and Body Composition in a Population of Overweight/Obese Adults: A Controlled Randomized Study. Nutrients 2023;15:5033
    https://doi.org/10.3390/nu15245033
  8. G. A. Mavondo, B. N. Mkhwananzi, M. V. Mabandla, C. T. Musabayane. Asiatic acid influences parasitaemia reduction and ameliorates malaria anaemia in P. berghei infected Sprague–Dawley male rats. BMC Complement Altern Med 2016;16
    https://doi.org/10.1186/s12906-016-1338-z
  9. Edward G Walker, Kim R Lo, Malcolm C Pahl, Hyun S Shin, Claudia Lang, Mark W Wohlers, Sally D Poppitt, Kevin H Sutton, John R Ingram. An extract of hops (Humulus lupulus L.) modulates gut peptide hormone secretion and reduces energy intake in healthy-weight men: a randomized, crossover clinical trial. The American Journal of Clinical Nutrition 2022;115:925
    https://doi.org/10.1093/ajcn/nqab418
  10. Tim Klaassen, Daniel Keszthelyi, Freddy J. Troost, Aalt Bast, Adrian A. M. Masclee. Effects of gastrointestinal delivery of non-caloric tastants on energy intake: a systematic review and meta-analysis. Eur J Nutr 2021;60:2923
    https://doi.org/10.1007/s00394-021-02485-4
  11. E. Deloose, M. Corsetti, L. Van Oudenhove, I. Depoortere, J. Tack. Intragastric infusion of the bitter tastant quinine suppresses hormone release and antral motility during the fasting state in healthy female volunteers. Neurogastroenterology Motil 2018;30
    https://doi.org/10.1111/nmo.13171
  12. Edward Walker, Kim Lo, Pramod Gopal. Gastrointestinal delivery of bitter hop extract reduces appetite and food cravings in healthy adult women undergoing acute fasting. Obesity Pillars 2024;11:100117
    https://doi.org/10.1016/j.obpill.2024.100117
  13. Qiaoling Wang, Kathrin I. Liszt, Inge Depoortere. Extra-oral bitter taste receptors: New targets against obesity?. Peptides 2020;127:170284
    https://doi.org/10.1016/j.peptides.2020.170284
  14. Vida Bitarafan, Penelope C.E. Fitzgerald, Sally D. Poppitt, John R. Ingram, Christine Feinle-Bisset. Effects of intraduodenal or intragastric administration of a bitter hop extract (Humulus lupulus L.), on upper gut motility, gut hormone secretion and energy intake in healthy-weight men. Appetite 2023;184:106490
    https://doi.org/10.1016/j.appet.2023.106490
  15. Tim Klaassen, Daniel Keszthelyi, Annick M. E. Alleleyn, Ellen Wilms, Aalt Bast, Adrian A. M. Masclee, Freddy J. Troost. Effect of oral or intragastric delivery of the bitter tastant quinine on food intake and appetite sensations: a randomised crossover trial. Br J Nutr 2021;125:92
    https://doi.org/10.1017/S0007114520002536
  16. Moon Young Yang, Amirhossein Mafi, Soo-Kyung Kim, William A. Goddard, Brian Guthrie. Predicted structure of fully activated human bitter taste receptor TAS2R4 complexed with G protein and agonists. QRB Discovery 2021;2
    https://doi.org/10.1017/qrd.2021.1
  17. Vida Bitarafan, Penelope C E Fitzgerald, Tanya J Little, Wolfgang Meyerhof, Tongzhi Wu, Michael Horowitz, Christine Feinle-Bisset. Effects of Intraduodenal Infusion of the Bitter Tastant, Quinine, on Antropyloroduodenal Motility, Plasma Cholecystokinin, and Energy Intake in Healthy Men. J Neurogastroenterol Motil 2019;25:413
    https://doi.org/10.5056/jnm19036
  18. Braden D Rose, Vida Bitarafan, Peyman Rezaie, Penelope C E Fitzgerald, Michael Horowitz, Christine Feinle-Bisset. Comparative Effects of Intragastric and Intraduodenal Administration of Quinine on the Plasma Glucose Response to a Mixed-Nutrient Drink in Healthy Men: Relations with Glucoregulatory Hormones and Gastric Emptying. The Journal of Nutrition 2021;151:1453
    https://doi.org/10.1093/jn/nxab020
  19. Gisela Olias, Maik Behrens, Gaby Andersen, Veronika Somoza. Nahrungsinhaltsstoffe: Chemorezeptor-vermitteltes pharmakonutritives Potenzial. Ernährung & Medizin 2022;37:133
    https://doi.org/10.1055/a-1856-9234
  20. Luke Hassan, Lisa Newman, Russell Keast, Jessica Danaher, Jessica R. Biesiekierski. The effect of gastrointestinal bitter sensing on appetite regulation and energy intake: A systematic review. Appetite 2023;180:106336
    https://doi.org/10.1016/j.appet.2022.106336
  21. Joan Serrano, Àngela Casanova-Martí, M. Teresa Blay, Ximena Terra, Montserrat Pinent, Anna Ardévol. Strategy for limiting food intake using food components aimed at multiple targets in the gastrointestinal tract. Trends in Food Science & Technology 2017;68:113
    https://doi.org/10.1016/j.tifs.2017.08.002
  22. Luigi Barrea, Giuseppe Annunziata, Giovanna Muscogiuri, Angela Arnone, Gian Carlo Tenore, Annamaria Colao, Silvia Savastano. Could hop-derived bitter compounds improve glucose homeostasis by stimulating the secretion of GLP-1?. Critical Reviews in Food Science and Nutrition 2019;59:528
    https://doi.org/10.1080/10408398.2017.1378168
  23. Milan Nagy, Pavel Mučaji. Cellular and molecular mechanisms of action of bitter compounds: recent knowledge and perspective. Čes. slov. farm. 2016;65:132
    https://doi.org/10.36290/csf.2016.029
  24. Yu-xin Zhang, Xing Wang, Shi-feng Wang, Yan-Ling Zhang, Yan-Jiang Qiao. Traditional Chinese Bitter Flavor theory: Is there any relation with taste type II receptors?. European Journal of Integrative Medicine 2016;8:980
    https://doi.org/10.1016/j.eujim.2016.04.011
  25. Vida Bitarafan, Penelope C. E. Fitzgerald, Tanya J. Little, Wolfgang Meyerhof, Karen L. Jones, Tongzhi Wu, Michael Horowitz, Christine Feinle-Bisset. Intragastric administration of the bitter tastant quinine lowers the glycemic response to a nutrient drink without slowing gastric emptying in healthy men. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2020;318:R263
    https://doi.org/10.1152/ajpregu.00294.2019
  26. Lindsey A. Schier, Alan C. Spector. The Functional and Neurobiological Properties of Bad Taste. Physiological Reviews 2019;99:605
    https://doi.org/10.1152/physrev.00044.2017
  27. Sara Rurgo, Elena Cantone, Marcella Pesce, Eleonora Efficie, Mario Musella, Barbara Polese, Barbara De Conno, Marta Pagliaro, Luisa Seguella, Bruna Guida, Giuseppe Esposito, Giovanni Sarnelli. Sleeve Gastrectomy-Induced Body Mass Index Reduction Increases the Intensity of Taste Perception’s and Reduces Bitter-Induced Pleasantness in Severe Obesity. JCM 2022;11:3957
    https://doi.org/10.3390/jcm11143957
  28. Peyman Rezaie, Vida Bitarafan, Michael Horowitz, Christine Feinle-Bisset. Effects of Bitter Substances on GI Function, Energy Intake and Glycaemia-Do Preclinical Findings Translate to Outcomes in Humans?. Nutrients 2021;13:1317
    https://doi.org/10.3390/nu13041317
  29. Tim Klaassen, Annick M. E. Alleleyn, Mark van Avesaat, Freddy J. Troost, Daniel Keszthelyi, Adrian A. M. Masclee. Intraintestinal Delivery of Tastants Using a Naso-Duodenal-Ileal Catheter Does Not Influence Food Intake or Satiety. Nutrients 2019;11:472
    https://doi.org/10.3390/nu11020472
  30. Giovanni Sarnelli, Giuseppe Annunziata, Silvia Magno, Claudia Oriolo, Silvia Savastano, Annamaria Colao. Taste and the Gastrointestinal tract: from physiology to potential therapeutic target for obesity. Int J Obes Supp 2019;9:1
    https://doi.org/10.1038/s41367-019-0012-6
  31. Carolina R. Cawthon, Claire B. de La Serre. The critical role of CCK in the regulation of food intake and diet-induced obesity. Peptides 2021;138:170492
    https://doi.org/10.1016/j.peptides.2020.170492
  32. Peyman Rezaie, Vida Bitarafan, Braden David Rose, Kylie Lange, Zinat Mohammadpour, Jens Frederik Rehfeld, Michael Horowitz, Christine Feinle-Bisset. Effects of Quinine on the Glycaemic Response to, and Gastric Emptying of, a Mixed-Nutrient Drink in Females and Males. Nutrients 2023;15:3584
    https://doi.org/10.3390/nu15163584
  33. Julie Iven, Jessica R. Biesiekierski, Dongxing Zhao, Eveline Deloose, Owen G. O’Daly, Inge Depoortere, Jan Tack, Lukas Van Oudenhove. Intragastric quinine administration decreases hedonic eating in healthy women through peptide-mediated gut-brain signaling mechanisms. Nutritional Neuroscience 2019;22:850
    https://doi.org/10.1080/1028415X.2018.1457841
  34. Alexandria Turner, Martin Veysey, Simon Keely, Christopher J. Scarlett, Mark Lucock, Emma L. Beckett. Intense Sweeteners, Taste Receptors and the Gut Microbiome: A Metabolic Health Perspective. IJERPH 2020;17:4094
    https://doi.org/10.3390/ijerph17114094
  35. Camilla Cattaneo, Chiara Mameli, Enza D'Auria, Gianvincenzo Zuccotti, Ella Pagliarini. The Influence of Common Noncommunicable Diseases on Chemosensory Perception and Clinical Implications in Children and Adolescents. Advances in Nutrition 2022;13:234
    https://doi.org/10.1093/advances/nmab100
  36. Saeed Shoar, Mohammad Naderan, Nasrin Shoar, Venkat R. Modukuru, Habibollah Mahmoodzadeh. Alteration Pattern of Taste Perception After Bariatric Surgery: a Systematic Review of Four Taste Domains. OBES SURG 2019;29:1542
    https://doi.org/10.1007/s11695-019-03730-w
  37. Kamila Tuzim, Agnieszka Korolczuk. An update on extra-oral bitter taste receptors. J Transl Med 2021;19
    https://doi.org/10.1186/s12967-021-03067-y
  38. Elisabet Garcia-Puig, Fan Liu, Rebecca Morrison, Maximiliano Müller, Allan Lisle, Eugeni Roura, Dana Campbell. Bitter compound quinine hydrochloride improved post-weaning pig performance in the absence of zinc oxide. Anim. Prod. Sci. 2024;64
    https://doi.org/10.1071/AN24201
  39. Szilvia Czigle, Silvia Bittner Fialová, Jaroslav Tóth, Pavel Mučaji, Milan Nagy. Treatment of Gastrointestinal Disorders—Plants and Potential Mechanisms of Action of Their Constituents. Molecules 2022;27:2881
    https://doi.org/10.3390/molecules27092881
  40. Ilario Mennella, Vincenzo Fogliano, Rosalia Ferracane, Marco Arlorio, Franco Pattarino, Paola Vitaglione. Microencapsulated bitter compounds (from Gentiana lutea) reduce daily energy intakes in humans. Br J Nutr 2016;116:1841
    https://doi.org/10.1017/S0007114516003858
  41. Harry P.F. Peters, Wieneke Koppenol, Ewoud A.H. Schuring, Robin Gouka, David J. Mela, Wendy A.M. Blom. The effect of two weeks ingestion of a bitter tastant mixture on energy intake in overweight females. Appetite 2016;107:268
    https://doi.org/10.1016/j.appet.2016.08.013
  42. Fei Xie, Jiakun Shen, Tianyi Liu, Min Zhou, Lee J. Johnston, Jingwen Zhao, Hongfu Zhang, Xi Ma. Sensation of dietary nutrients by gut taste receptors and its mechanisms. Critical Reviews in Food Science and Nutrition 2023;63:5594
    https://doi.org/10.1080/10408398.2021.2021388
  43. Wout Verbeure, Eveline Deloose, Joran Tóth, Jens F. Rehfeld, Lukas Van Oudenhove, Inge Depoortere, Jan Tack. The endocrine effects of bitter tastant administration in the gastrointestinal system: intragastric versus intraduodenal administration. American Journal of Physiology-Endocrinology and Metabolism 2021;321:E1
    https://doi.org/10.1152/ajpendo.00636.2020
  44. Betsy Cogan, Jamie A. Cooper. Differential effects of nutritive and non-nutritive sweet mouth rinsing on appetite in adults with obesity. Appetite 2024;193:107133
    https://doi.org/10.1016/j.appet.2023.107133
  45. Cong Xie, Xuyi Wang, Richard L. Young, Michael Horowitz, Christopher K. Rayner, Tongzhi Wu. Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control. Front. Endocrinol. 2018;9
    https://doi.org/10.3389/fendo.2018.00576
  46. Greanious Alfred Alfrd Mavondo, Musabayane Cephas Tagumirwa. Asiatic acid-pectin hydrogel matrix patch transdermal delivery system influences parasitaemia suppression and inflammation reduction in P. berghei murine malaria infected Sprague–Dawley rats. Asian Pacific Journal of Tropical Medicine 2016;9:1172
    https://doi.org/10.1016/j.apjtm.2016.10.008
  47. Hee Man Kim. Modulation of the Bitter Taste to Reduce Calorie Intake. J Neurogastroenterol Motil 2015;21:457
    https://doi.org/10.5056/jnm15142
  48. Christina M. Hochkogler, Kathrin Liszt, Barbara Lieder, Verena Stöger, Anna Stübler, Marc Pignitter, Joachim Hans, Sabine Widder, Jakob P. Ley, Gerhard E. Krammer, Veronika Somoza. Appetite‐Inducing Effects of Homoeriodictyol: Two Randomized, Cross‐Over Interventions. Molecular Nutrition Food Res 2017;61
    https://doi.org/10.1002/mnfr.201700459
  49. Verena Stoeger, Ann-Katrin Holik, Kathrin Hölz, Tamir Dingjan, Joachim Hans, Jakob P. Ley, Gerhard E. Krammer, Masha Y. Niv, Mark Manuel Somoza, Veronika Somoza. Bitter-Tasting Amino Acids l-Arginine and l-Isoleucine Differentially Regulate Proton Secretion via T2R1 Signaling in Human Parietal Cells in Culture. J. Agric. Food Chem. 2020;68:3434
    https://doi.org/10.1021/acs.jafc.9b06285
  50. Xinyue Zhou, Han Wang, Ming Huang, Jin Chen, Jianle Chen, Huan Cheng, Xingqian Ye, Wenjun Wang, Donghong Liu. Role of bitter contributors and bitter taste receptors: a comprehensive review of their sources, functions and future development. 2024;13:1806
    https://doi.org/10.26599/FSHW.2022.9250151
  51. Naomi Osakabe, Makoto Ohmoto, Takafumi Shimizu, Naoki Iida, Taiki Fushimi, Yasuyuki Fujii, Keiko Abe, Vittorio Calabrese. Gastrointestinal hormone-mediated beneficial bioactivities of bitter polyphenols. Food Bioscience 2024;61:104550
    https://doi.org/10.1016/j.fbio.2024.104550
  52. Catia Sternini, Enrique Rozengurt. Bitter taste receptors as sensors of gut luminal contents. Nat Rev Gastroenterol Hepatol 2025;22:39
    https://doi.org/10.1038/s41575-024-01005-z
  53. Vida Bitarafan, Javad Anjom-Shoae, Peyman Rezaie, Penelope C. E. Fitzgerald, Kylie Lange, Michael Horowitz, Christine Feinle-Bisset. Dose-related effects of intraduodenal quinine on plasma glucose, glucoregulatory hormones and gastric emptying of a nutrient drink, and energy intake, in men with type 2 diabetes: a double-blind, randomised, crossover study. Diabetologia 2024
    https://doi.org/10.1007/s00125-024-06344-9
  54. Peyman Rezaie, Vida Bitarafan, Braden D Rose, Kylie Lange, Jens F Rehfeld, Michael Horowitz, Christine Feinle-Bisset. Quinine Effects on Gut and Pancreatic Hormones and Antropyloroduodenal Pressures in Humans–Role of Delivery Site and Sex. 2022;107:e2870
    https://doi.org/10.1210/clinem/dgac182