• What Is New in Rome IV

    Frequency of reporting of pain or burning above the belly button in the normative survey. The histograms show the frequency of reporting in different time frames for men, women and the combined sample. The vertical dotted line shows the 90th percentile for the combined sample of females and males. MT shows the minimum threshold in males and FT shows the minimum 90th percentile in females. Accordingly, a threshold of only 2–3 days a month would limit misclassification to 10% in females, whereas a threshold of 1 day/ month would limit misclassification to 10% in males. Reproduced with permission from Rome Foundation, Inc.

  • Emerging Roles of the Endolumenal Functional Lumen Imaging Probe in Gastrointestinal Motility Disorders

    Components of the endolumenal functional lumen imaging probe (EndoFLIP; EF100) system. (A) There is a catheter connector that connects the syringe which is held by a syringe door and lock to the catheter. There are several catheters but the most common is EF-325 (for description, see B). The recording unit has a touchscreen display with a primary user interface (for description, see C). (B) The catheter (EF-325N) is a 240 cm long plastic catheter with a polyurethrane balloon at its distal end with a maximum diameter of 2.5 cm. Conductive medium fills the balloon during inflation, and within the balloon there are 17 impedance electrodes within a 8 cm segment. Ref is midpoint of the balloon catheter. (C) The display has a friendly touchscreen interface that includes injection volume controls, live images of the balloon inflation and a status window.

  • Control of Food Intake by Gastrointestinal Peptides: Mechanisms of Action and Possible Modulation in the Treatment of Obesity

    Effects of gastrointestinal peptides on food intake via the gut-brain axis. The left side shows the anorexigenic signaling pathway, whereas orexigenic signaling is shown on the right panel. PVN, paraventricular nucleus; LHA, lateral hypothalamic area; MCR 3/4, melanocortin receptors 3 and 4; ARC, arcuate nucleus; POMC, pro-opiomelanocortin; CART, cocaine-and amphetamine-regulatory transcript; NPY, neuropeptide Y; AgRP, agouti-related peptide; NTS, nucleus of the solitary tract; Y1, NPY receptor 1; GIT, gastrointestinal tract; PYY, peptide tyrosine tyrosine; GLP-1, glucagon-like peptide 1; NF-1, nesfatin-1; CCK, cholecystokinin; ↓, decrease; ↑, increase; ?, controversial data (NF-1) or data that resulted from mimetics (GLP-1).

  • How to Perform and Interpret Functional Magnetic Resonance Imaging Studies in Functional Gastrointestinal Disorders

    Example of hemodynamic response (A) and time series blood oxygen level dependent (BOLD) signal from a voxel (B). (A) Neurons respond rapidly to internal or external changes and allow the alterations of blood flow and oxygenation in the close area (hemodynamic response) that drives the peak of BOLD signal few seconds after the onset of internal or external changes. BOLD signal slowly returns to baseline level following an undershoot. (B) Within the field of view, each slice consists of a certain number of voxels determined by the size of the measurement matrix. The BOLD signal of each voxel is recorded at consecutive time points and this time trace is further analysed to interfere with functional brain activation.


Journal of Neurogastroenterology and Motility 2017; 23(2): 145~319
Editorials
Can Nocturnal Acid-breakthrough Be Reduced by Long-acting Proton Pump Inhibitors?
Hye Kyung Jeon, and Gwang Ha Kim
Journal of Neurogastroenterology and Motility 2017; 23(2): 145-148  https://doi.org/10.5056/jnm17037
Clinical Usefulness of Fecal Microbiota Transplantation
Jung Ho Park
Journal of Neurogastroenterology and Motility 2017; 23(2): 149-150  https://doi.org/10.5056/jnm17024
Reviews
What Is New in Rome IV
Max J Schmulson, and Douglas A Drossman
Journal of Neurogastroenterology and Motility 2017; 23(2): 151-163  https://doi.org/10.5056/jnm16214
Emerging Roles of the Endolumenal Functional Lumen Imaging Probe in Gastrointestinal Motility Disorders
Rona M Ata-Lawenko, and Yeong Yeh Lee
Journal of Neurogastroenterology and Motility 2017; 23(2): 164-170  https://doi.org/10.5056/jnm16171
Future Treatment of Constipation-associated Disorders: Role of Relamorelin and Other Ghrelin Receptor Agonists
Paula Mosińska, Hubert Zatorski, Martin Storr, and Jakub Fichna
Journal of Neurogastroenterology and Motility 2017; 23(2): 171-179  https://doi.org/10.5056/jnm16183
Control of Food Intake by Gastrointestinal Peptides: Mechanisms of Action and Possible Modulation in the Treatment of Obesity
Philip Prinz, and Andreas Stengel
Journal of Neurogastroenterology and Motility 2017; 23(2): 180-196  https://doi.org/10.5056/jnm16194
Technique Review
How to Perform and Interpret Functional Magnetic Resonance Imaging Studies in Functional Gastrointestinal Disorders
In-Seon Lee, Hubert Preissl, and Paul Enck
Journal of Neurogastroenterology and Motility 2017; 23(2): 197-207  https://doi.org/10.5056/jnm16196
Original Articles
Esophageal Acidification During Nocturnal Acid-breakthrough with Ilaprazole Versus Omeprazole in Gastroesophageal Reflux Disease
Arun Karyampudi, Uday C Ghoshal, Rajan Singh, Abhai Verma, Asha Misra, and Vivek A Saraswat
Journal of Neurogastroenterology and Motility 2017; 23(2): 208-217  https://doi.org/10.5056/jnm16087
A Double-blind, Randomized, Multicenter Clinical Trial Investigating the Efficacy and Safety of Esomeprazole Single Therapy Versus Mosapride and Esomeprazole Combined Therapy in Patients with Esophageal Reflux Disease
Ju Yup Lee, Sung Kook Kim, Kwang Bum Cho, Kyung Sik Park, Joong Goo Kwon, Jin Tae Jung, Eun Young Kim, Byung Ik Jang, Si Hyung Lee, and
Journal of Neurogastroenterology and Motility 2017; 23(2): 218-228  https://doi.org/10.5056/jnm16100
Effects of Age on Esophageal Motility: Use of High-resolution Esophageal Impedance Manometry
Young Kwang Shim, Nayoung Kim, Yo Han Park, Jong-Chan Lee, Jihee Sung, Yoon Jin Choi, Hyuk Yoon, Cheol Min Shin, Young Soo Park, and Dong Ho Lee
Journal of Neurogastroenterology and Motility 2017; 23(2): 229-236  https://doi.org/10.5056/jnm16104
The Relationship of the Post-reflux Swallow-induced Peristaltic Wave Index and Esophageal Baseline Impedance with Gastroesophageal Reflux Disease Symptoms
Young Kyu Cho, Joon Seong Lee, Tae Hee Lee, Su Jin Hong, Sang Joon Park, Seong Ran Jeon, Hyun Gun Kim, and Jin-Oh Kim
Journal of Neurogastroenterology and Motility 2017; 23(2): 237-244  https://doi.org/10.5056/jnm16115
Central and Peripheral Effects of Transcutaneous Acupuncture Treatment for Nausea in Patients with Diabetic Gastroparesis
Irene Sarosiek, Gengqing Song, Yan Sun, Hugo Sandoval, Stephen Sands, Jiande Chen, and Richard W McCallum
Journal of Neurogastroenterology and Motility 2017; 23(2): 245-253  https://doi.org/10.5056/jnm16097
The Association Between Fasting C-peptide and Gastrointestinal Symptoms of Gastroparesis in Type 2 Diabetic Patients
Yun Huang, Honghong Zhang, Minxia Zhang, Wenya Li, Jinhua Wang, and Ji Hu
Journal of Neurogastroenterology and Motility 2017; 23(2): 254-261  https://doi.org/10.5056/jnm16091
Assessment of the Asian Neurogastroenterology and Motility Association Chronic Constipation Criteria: An Asian Multicenter Cross-sectional Study
Kok-Ann Gwee, Paul Bergmans, JinYong Kim, Bogdana Coudsy, Angelia Sim, Minhu Chen, Lin Lin, Xiaohua Hou, Huahong Wang, Khean-Lee Goh, John A Pangilinan, Nayoung Kim, and Stanislas Bruley des Varannes
Journal of Neurogastroenterology and Motility 2017; 23(2): 262-272  https://doi.org/10.5056/jnm16095
Chronic Intestinal Pseudo-obstruction: Clinical and Manometric Characteristics in the Chilean Population
Edith Pérez de Arce, Glauben Landskron, Sandra Hirsch, Carlos Defilippi, and Ana María Madrid
Journal of Neurogastroenterology and Motility 2017; 23(2): 273-280  https://doi.org/10.5056/jnm16101
Maturation Phenotype of Peripheral Blood Monocyte/Macrophage After Stimulation with Lipopolysaccharides in Irritable Bowel Syndrome
Oscar A Rodríguez-Fandiño, Joselín Hernández-Ruiz, Yolanda López-Vidal, Luis Charúa-Guindic, Galileo Escobedo, and Max J Schmulson
Journal of Neurogastroenterology and Motility 2017; 23(2): 281-288  https://doi.org/10.5056/jnm16137
Serial Frozen Fecal Microbiota Transplantation in the Treatment of Chronic Intestinal Pseudo-obstruction: A Preliminary Study
Lili Gu, Chao Ding, Hongliang Tian, Bo Yang, Xuelei Zhang, Yue Hua, Yifan Zhu, Jianfeng Gong, Weiming Zhu, Jieshou Li, and Ning Li
Journal of Neurogastroenterology and Motility 2017; 23(2): 289-297  https://doi.org/10.5056/jnm16074
Association Between Excessive Daytime Sleepiness and Functional Gastrointestinal Disorders: A Population-based Study in China
Sicheng Wu, Shuqi Chen, Yanfang Zhao, Xiuqiang Ma, Rui Wang, and Jia He
Journal of Neurogastroenterology and Motility 2017; 23(2): 298-305  https://doi.org/10.5056/jnm16056
Maternal Separation Induced Visceral Hypersensitivity from Childhood to Adulthood
Lisha Yi, Haiqin Zhang, Huihui Sun, Lu Zhou, Ying Chen, Liqian Xuan, Yuanxi Jiang, and Shuchang Xu
Journal of Neurogastroenterology and Motility 2017; 23(2): 306-315  https://doi.org/10.5056/jnm16089
Letter to the Editor
The Evidence of DA-9701 on Bowel Motility
Mingjie Wang, Jianlin Lv, and Meng Xia
Journal of Neurogastroenterology and Motility 2017; 23(2): 316-317  https://doi.org/10.5056/jnm17011
Relevance of Measuring Substances in Bronchoalveolar Lavage Fluid for Detecting Aspiration-associated Extraesophageal Reflux Disease
Edoardo Savarino, Patrizia Zentilin, Elisa Marabotto, and Vincenzo Savarino
Journal of Neurogastroenterology and Motility 2017; 23(2): 318-319  https://doi.org/10.5056/jnm17027

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Current Issue

April 2017
Volume 23
Issue 2
  • News & Notice
  • Yong Sung Kim
    Department of Gastroenterology, Digestive Disease Research Institute, Wonkwang University Sanbon Hospital, Gunpo, Korea
  • Yang Won Min
    Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
  • Ching-Liang Lu
    Division of Gastroenterology, Taipei Veterans General Hospital, National Yang-Ming University Taipei, Taiwan
  • Jae Yeoul Jun
    Department of Physiology, Chosun University School of Medicine, Gwangju, Korea
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The aim of the Journal is to foster and promote research activities on the area of the motor, sensory and functional disorders of gastrointestinal tract. The Journal provides researchers with accessible rooms for publication of their research results in the field of neuroga- stroenterology and motility. more
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