J Neurogastroenterol Motil 2012; 18(1): 70-77  https://doi.org/10.5056/jnm.2012.18.1.70
Gender Role in Irritable Bowel Syndrome: A Comparison of Irritable Bowel Syndrome Module (ROME III) Between Male and Female Patients
Sanam Javid Anbardan1, Nasser Ebrahimi Daryani1*, Seyed-Mohammad Fereshtehnejad2, Sahar Taba Taba Vakili3, Mohammad Reza Keramati4 and Hossein Ajdarkosh5

1Department of Gastroenterology and Hepatology, Tehran University of Medical Sciences, Tehran, Iran.

2Gastrointestinal and Liver Disease Research Center (GILDRC), Firoozgar Clinical Research Development Center, Tehran University of Medical Sciences, Tehran, Iran.

3Department of Internal Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran.

5Gastrointestinal & Liver Disease Research Center (GILDRC), Tehran University of Medical Sciences, Tehran, Iran.

Correspondence to: Correspondence: Nasser Ebrahimi Daryani, MD. Division of Gastroenterology, Department of Gastroenterology and Hepatology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Tel: +98-21-8879-9446, Fax: +98-21-8879-7611-9, nasere@yahoo.com
Received: July 14, 2011; Revised: September 4, 2011; Accepted: September 6, 2011; Published online: January 16, 2012.
© The Korean Society of Neurogastroenterology and Motility. All rights reserved.

cc This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract

Background/Aims

Irritable bowel syndrome (IBS) is a widespread chronic health condition which is significantly more prevalent in women. We conducted a gender difference analysis by comparing findings of men and women to determine whether any significant differences exist or not.

Methods

This single-center study was conducted in Tehran, Iran during 2009-2010. IBS was diagnosed on the basis of Rome III criteria. A simple "10 point" objective questionnaire was used.

Results

A total number of 144 IBS patients including 44 (30.6%) males and 100 (69.4%) females with the mean age of 37.50 ± 11.50 years, were assessed. The only differently observed symptom was nausea which was significantly more prevalent in females (49% vs 18.2%, < 0.001). The commonest subtype of IBS in male patients was diarrhea predominant IBS (38.6%); while, constipation predominant IBS was the most frequent type among females (38%). Moreover, the frequency of loose, mushy or watery stools within the last 3 months was significantly higher among males (2.11 ± 1.67 vs 1.37 ± 1.50, = 0.009).

Conclusions

We report that gender is important in IBS. Although qualitative comparison of different subtypes of IBS between male and female failed to meet the statistically significant level, the answers to the corresponding questions of ROME III IBS module suggest the higher prevalence of bowel movements and looser stool in males. Moreover, nausea was reported more often by females.

Keywords: Gender identity, Irritable bowel syndrome, Questionnaire, ROME III


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