J Neurogastroenterol Motil  
Psychiatric Comorbidity in Patients With Irritable Bowel Syndrome at a Tertiary Care Center in Northern India
Yuman Kawoos,1* Zaid A Wani,1 Showkat A Kadla,2 Irfan A Shah,3 Arshad Hussain,1 M Maqbool Dar,1 Mushtaq A Margoob,1 and Kouser Sideeq4
Departments of 1Psychiatry, 2Gastroenterology, 4Preventive and Social Medicine, Government Medical College Srinagar, Srinagar, Jammu and Kashimir, India; and 3Department of Neurology, Sheri-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India
Correspondence to: Yuman Kawoos, MD
Department of Psychiatry, Government Psychiatric Diseases Hospital Srinagar, G1, Residential block, Srinagar, Jammu and Kashmir 190003, India
Tel: +91-9419405478, Fax: +91-9419009329, E-mail: yumankawoos@ymail.com
Received: October 13, 2016; Revised: March 21, 2017; Accepted: April 2, 2017; Published online: July 21, 2017.
© The Korean Society of Neurogastroenterology and Motility. All rights reserved.

cc This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background/Aims
Irritable bowel syndrome (IBS) is a chronic psycho-physiological disorder. It is considered to be the most common functional gastrointestinal disorder, and about 50.0-90.0% of IBS patients have associated psychiatric comorbidity. We aimed to study psychiatric comorbidities in patients with IBS visiting a tertiary care center.
Methods
This was a cross-sectional case-control study conducted over a duration of one and a half years from January 2014 to July 2015. Patients were selected from the out-patient department of gastroenterology. About 160 patients with IBS who fulfilled the inclusion criteria and who gave written informed consent were selected as study cases. The healthy attendants of cases were selected as controls. A total of 200 controls were selected. Rome-III criteria were used to diagnose IBS. For diagnosing psychiatric disorders, we used the Mini International Neuropsychiatric Interview Schedule Plus.
Results
Mean age of our cases and controls was 39.7 ± 11.4 and 37.7 ± 9.6 years, respectively. Females outnumbered males in our cases as well as their controls by a ratio of 2:1 approximately. Psychiatric disorders were seen in 84.4% of IBS patients as compared to 41.5% in controls. Major psychiatric disorders seen in our patients were generalized anxiety disorders (30.0%) and depression (28.0%).
Conclusions
The majority of patients with IBS who present to a tertiary care center have comorbid psychiatric disorders. We need to screen these patients for such comorbidities and develop a holistic approach for better outcome in such cases.
Keywords: Anxiety disorder; Comorbidity; Depression; Gastrointestinal diseases; Irritable bowel syndrome


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