J Neurogastroenterol Motil  
Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia
Asano Haruki,1 Toshihiko Tomita,1 Kumiko Nakamura,1 Takahisa Yamasaki,1 Takuya Okugawa,1 Takashi Kondo,1 Tomoaki Kono,1 Katsuyuki Tozawa,1 Yoshio Ohda,1 Tadayuki Oshima,1 Hirokazu Fukui,1 Kazuhito Fukushima,2 Shozo Hirota,3 Jiro Watari,1 and Hiroto Miwa1*
1Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan; and 2Division of Nuclear Medicine and PET Center, 3Department of Radiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
Correspondence to: Hiroto Miwa, MD, PhD
Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine 1-1, Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan
Tel: +81-798-45-6665, Fax: +81-798-45-6661, E-mail: miwahgi@hyo-med.ac.jp
Received: October 13, 2016; Revised: January 14, 2017; Accepted: February 8, 2017; Published online: April 19, 2017.
© The Korean Society of Neurogastroenterology and Motility. All rights reserved.

cc This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background/Aims
Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of this study are to (1) investigate the prevalence of gastric motility disorders and (2) evaluate the association between gastric motility abnormalities and dyspeptic symptoms using gastric scintigraphy in the PDS type of FD.
Methods
Forty healthy subjects and 94 PDS type FD patients were enrolled in the study. The volunteers and patients ingested a radiolabeled (technetium-99m) solid test meal, and scintigraphic images were recorded. Gastric accommodation and emptying were assessed by scintigraphic imaging. The patients’ dyspeptic symptoms were also explored using self-completed symptom questionnaires with 10 variables (4 scales, 0-3 points) at the same time.
Results
In 94 Japanese FD patients, the prevalence of impaired gastric accommodation and delayed emptying were 14.9% (14/94) and 10.6% (10/94), respectively. Gastric motility abnormalities were seen in 25.5% (24/94) of FD patients. There was no association between gastric motility abnormalities and dyspeptic symptoms.
Conclusions
Gastric motility abnormalities were seen in 25.5% of Japanese PDS type FD patients. However, there was no association between gastric motility abnormalities and dyspeptic symptoms on gastric scintigraphy.
Keywords: Dyspepsia; Motility; Prevalence; Stomach


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