J Neurogastroenterol Motil  
Emerging roles of the Endolumenal Functional Lumen Imaging Probe (EndoFLIP) in Gastrointestinal Motility Disorders
Rona Marie A Lawenko1 and Yeong Yeh Lee2,*
1Section of Gastroenterology, De La Salle Health Sciences Institute, Dasmarinas City, Cavite, Philippines,
2School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia
Correspondence to: Yeong Yeh Lee, MD, PhD, FACP, FRCP, FACG
School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
Tel: +60-179028147, Fax: +60-97673949, E-mail:
Received: October 13, 2016; Accepted: November 20, 2016; Published online: December 23, 2016.
© The Korean Society of Neurogastroenterology and Motility. All rights reserved.

cc This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Gastrointestinal sphincters play a vital role in gut function and motility by separating the gut into functional segments. Traditionally, function of sphincters including the esophagogastric junction is studied using endoscopy and manometry. However, due to its dynamic biomechanical properties, data on distensibility and compliance may provide a more accurate representation of the sphincter function. The endolumenal functional lumen imaging probe (EndoFLIP) system uses a multi-detector impedance planimetry system to provide data on tissue distensibility and geometric changes in the sphincter as measured through resistance to volumetric distention with real-time images. With the advent of EndoFLIP studies, esophagogastric junction dysfunction and other disorders of the stomach and bowels may be better evaluated. It may be utilized as a tool in predicting effectiveness of endoscopic and surgical treatments as well as patient outcomes.
Keywords: Compliance, Electric impedanc, Esophagogastric junction, Humans, Manometry


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