Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

Download original image
Fig. 1. Desmin immunohistochemistry (A, B) and neuron-specific enolase (NSE) immunohistochemistry (C-F). (A) Base, 15 weeks. Both circular and longitudinal muscle layers (cm and lm) are desmin immunoreactivity , but the longitudinal one is extremely thin. (B) Apex, 33 weeks. Both muscular layers are well developed, but the circular one is considerably wider than the longitudinal one. (C) Apex, 15 weeks. NSE immunoreactivity was present between the muscle layers in the form of an almost uninterrupted belt of cells (long arrows), corresponding to the myenteric ganglia. In contrast, at the submucous border of the circular layer, there were less numerous groups of NSE-immunoreactive cells (short arrows), corresponding submucous plexus (SMP) ganglia. Individual groups of NSE-immunoreactive cells were present within the cm as well (arrowheads). (D) Base, 18 weeks. Groups of myenteric plexus (MP) neurons extend rather deep into the cm (arrows). (E) Base, 22 weeks. Groups of neurons are rather numerous and very pleomorphic within the circular (short arrows), and slightly less numerous within the lm (long arrows). MP and SMP ganglia are also present. (F) Base, 33 weeks. Groups of neurons are present in the MP and SMP regions, and within the cm (short arrows) and lm (long arrows). sm, submucosa. Bar: A-D, F = 60 μm; E = 50 μm.
J Neurogastroenterol Motil 2021;27:127~133
© J Neurogastroenterol Motil