Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

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Fig. 1. Transient receptor potential ankyrin 1 (TRPA1) expression in the antral mucosa of patients with diarrhea-predominant irritable bowel syndrome (IBS-D) is elevated. TRPA1 (A) and transient receptor potential melastatin 8 (TRPM8) (B) mRNA expression in antral mucosal biopsies from healthy controls (HC; n = 23) and patients with IBS-D (n = 19). (C) Representative photomicrographs showing TRPA1 immunore-activity in the antral mucosa of a healthy control (left) and a patient with IBS-D (middle). The sections incubated with PBS instead of the primary antibody served as the negative control (NC; right). (D) Quantification of TRPA1 immunoreactivity using ImageJ software. *P < 0.05, **P < 0.01 (Student’s t test).
Journal of Neurogastroenterology and Motility 2019;25:442~460 https://doi.org/10.5056/jnm19014
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