Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

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Fig. 1. Effects of gastrointestinal peptides on food intake via the gut-brain axis. The left side shows the anorexigenic signaling pathway, whereas orexigenic signaling is shown on the right panel. PVN, paraventricular nucleus; LHA, lateral hypothalamic area; MCR 3/4, melanocortin receptors 3 and 4; ARC, arcuate nucleus; POMC, pro-opiomelanocortin; CART, cocaine-and amphetamine-regulatory transcript; NPY, neuropeptide Y; AgRP, agouti-related peptide; NTS, nucleus of the solitary tract; Y1, NPY receptor 1; GIT, gastrointestinal tract; PYY, peptide tyrosine tyrosine; GLP-1, glucagon-like peptide 1; NF-1, nesfatin-1; CCK, cholecystokinin; ↓, decrease; ↑, increase; ?, controversial data (NF-1) or data that resulted from mimetics (GLP-1).
Journal of Neurogastroenterology and Motility 2017;23:180~196 https://doi.org/10.5056/jnm16194
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