Journal of Neurogastroenterology and Motility : eISSN 2093-0887 / pISSN 2093-0879

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Fig. 2. Microbial analysis of the gut microbiota in each reactor at the 2 different simulated transit time. (A) On the upper part are indicated the biomass of dry matter (in gram per liter of medium) and the Shannon diversity index (characterizing the diversity in a community, ie, species abundance and evenness). *Corresponds to values obtained at the slow simulated transit time which are significantly different when compared to the values obtained in the same reactor at the normal simulated transit time (P < 0.05). The histogram below provides the proportion (in %) of each bacterial family detected by the Human Gut Chip (HuGChip). The legend is indicated in the left part (each color is representative of one phylum). (B) Correlation matrix based Principal Component Analysis of the microbial profiles obtained with the 3 reactors at the 2 simulated transit times. The 2 axes represent the 2 first components (ie, those that account for the more differences between samples, above 70% in this example), with the part (in %) they account for the overall observed difference across samples. Empty symbols, 48-hour transit time simulation; filled symbols, 96-hour transit time simulation; circles, proximal part; squares, transversal part; triangle, distal part. The arrows highlights the lower variability observed between compartments at a slower retention time compared with a normal one, when comparing the bacterial community differentiation from the proximal part to the distal one at the 2 transit times.
Journal of Neurogastroenterology and Motility 2017;23:124~134 https://doi.org/10.5056/jnm16042
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